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Pharmaceutical Powder Compaction Technology

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Compaction of powder constituents--both active ingredient and excipients--is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of <b>Pharmaceutical Powder Compaction Technology</b> guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. This unique reference covers: The physical structure of pharmaceutical compacts Bonding phenomena that occur during powder compaction Compression mechanisms of pharmaceutical particles Theories and basic principles of powder compaction New topics include: Compaction data analysis techniques The migration of powder constituents into commercial manufacture Instrumentation for compaction Compaction functionality testing, which is likely to become a USP requirement Design space for compaction Metrics required for scalability in tablet compression Interactive compaction and preformulation database for commonly used excipients

Buchkauf

Pharmaceutical Powder Compaction Technology, Metin Celik

Sprache
Erscheinungsdatum
2011
Einband
(Hardcover)
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Titel
Pharmaceutical Powder Compaction Technology
Sprache
Englisch
Autor*innen
Metin Celik
Verlag
CRC Press
Erscheinungsdatum
2011
Einband
Hardcover
Seitenzahl
344
ISBN10
142008917X
ISBN13
9781420089172
Reihe
Beschreibung
Compaction of powder constituents--both active ingredient and excipients--is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of <b>Pharmaceutical Powder Compaction Technology</b> guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. This unique reference covers: The physical structure of pharmaceutical compacts Bonding phenomena that occur during powder compaction Compression mechanisms of pharmaceutical particles Theories and basic principles of powder compaction New topics include: Compaction data analysis techniques The migration of powder constituents into commercial manufacture Instrumentation for compaction Compaction functionality testing, which is likely to become a USP requirement Design space for compaction Metrics required for scalability in tablet compression Interactive compaction and preformulation database for commonly used excipients