Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense research, spanning molecular and cellular biology, organic chemistry, cosmology, geology, and atmospheric science. Written and edited by experts in the field, this volume provides a comprehensive account of the environment of the early Earth and the mechanisms by which the organic molecules present may have self-assembled to form replicating material such as RNA and other polymers. The contributors examine the energetic requirements for this process and focus in particular on the essential role of semi-permeable compartments in containment of primitive genetic systems.
David W. Deamer Bücher
Continuing the tradition of its widely-praised previous editions, The World of the Cell, 7/e , covers some of the most difficult concepts for readers– bioinformatics, bioenergetics, metabolism, enzyme kinetics, thermodynamics, membrane transport, cell signaling, regulatory mechanisms, transcription and translation, signal transduction, and DNA replication and recombination–at the right level of depth and clarity. KEY TOPICS : A Preview of the Cell, The Chemistry of the Cell, The Macromolecules of the Cell, Cells and Organelles, Bioenergetics: The Flow of Energy in the Cell, Enzymes: The Catalysts of Life, Membranes: Their Structure, Function, and Chemistry, Transport Across Membranes: Overcoming the Permeability Barrier, Chemotrophic Energy Metabolism: Glycolysis and Fermentation, Chemotrophic Energy Metabolism: Aerobic Respiration, Phototrophic Energy Metabolism: Photosynthesis, The Endomembrane System and Peroxisomes, Signal Transduction Mechanisms: I. Electrical and Synaptic Signaling in Neurons, Signal Transduction Mechanisms: II. Messengers and Receptors, Cytoskeletal Systems, Cellular Movement: Motility and Contractility, Beyond the Cell: Cell Adhesion, Cell Junctions, and Extracellular Structures, The Structural Basis of Cellular Information: DNA, Chromosomes, and the Nucleus, The Cell Cycle, DNA Replication, and Mitosis, Sexual Reproduction, Meiosis, and Genetic Recombination, Gene Expression: I. The Genetic Code and Transcription, Gene Expression: II. Protein Synthesis and Sorting, The Regulation of Gene Expression, Cancer Cells, Principles and Techniques of Microscopy. MARKET : For all readers interested in molecular biology.