Diese Serie taucht in die Tiefen des Weltraums ein, wo die Menschheit durch mysteriöse Signale erstmals Kontakt mit außerirdischer Intelligenz aufnimmt. Das entdeckte Wissen, das aus einem außerirdischen Computer entschlüsselt wird, öffnet eine Büchse der Pandora des menschlichen Verständnisses. Wissenschaft und Technologie werden an ihre Grenzen gebracht, doch sie sehen sich auch einer Bedrohung gegenüber, die die bloße Existenz der Menschheit gefährden könnte.
A new radio telescope picks up from the constellation of Andromeda a complex series of signals which prove to be a programme for a giant computer. After the computer is built it begins to relay information from Andromeda. Scientists find themselves possessing knowledge previously unknown to mankind, knowledge that could threaten the security of human life itself.
The Andromeda Breakthrough is a sequel to the popular BBC TV science fiction serial A for Andromeda, written by Fred Hoyle and John Elliot. Kidnapped by Intel, John Fleming, the hero of the first serial, and Andromeda, the artificially constructed human, are brought to Azaran, a small Middle Eastern country, where a duplicate of the machine he designed has been built by Intel. After many dangers, he finds both the reason for the original message having been sent and the means to bring the machine under human control.