G protein coupled receptors as drug targets

Autor*innen

• Roland Seifert

Parameter

• Medizin & Gesundheit

Mehr zum Buch

This book offers an in-depth exploration of G-protein-coupled receptors (GPCRs), focusing on their constitutive activity, a topic not previously covered in such detail. An international team of esteemed authors presents current models and concepts, aimed at medicinal chemists, physiologists, pharmacologists, and medical researchers, highlighting advancements in understanding GPCR activation. It also outlines methods for investigating constitutive GPCR activity, supported by experimental data and illustrations. The chapters are cross-referenced, addressing general mechanisms, methodological approaches, and significant GPCR systems, while discussing the implications for drug action, including side effects and rational drug design for GPCR targets. The text is rich in case studies and methodological guidance, making it a practical reference for researchers in both academia and industry.

• Sprache: Englisch
• Erscheinungsdatum: 2005
• Einband: Hardcover