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Impedance cardiography allows for the estimation of stroke volume by injecting an alternating current into the body. This research introduces a wearable impedance cardiograph integrated into a shirt for home monitoring, utilizing conductive textile materials as electrodes and wiring. The garment connects to lightweight hardware that transmits data wirelessly, enabling continuous patient monitoring. Additionally, a 4D model of the human thorax and FEM simulations were used to analyze physiological sources contributing to the impedance waveform. Findings indicate that changes in blood conductivity due to red blood cell orientation significantly affect the impedance signal, with aortic wave propagation as a secondary factor. This model identified negative impacts of heart failure on measured impedance, corroborated by clinical trials, including a recompensation study and a pleural drainage study. Results revealed that increased lung conductivity from lung edema or pleural effusion leads to decreased impedance and lower stroke volume. Improved algorithms, specifically discrete wavelet transform, were developed to assess key points in the impedance cardiogram, outperforming those in existing commercial devices. Furthermore, human trials explored new applications, demonstrating the feasibility of using impedance cardiography to estimate blood alcohol content and assess stroke volume in sport divers during various stages of apnea.
Buchkauf
Non-invasive stroke volume assessment using the thoracic electrical bioimpedance, Mark Ulbrich
- Sprache
- Erscheinungsdatum
- 2016
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- Gratis Versand in ganz Deutschland!
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