Gustavo Oliveira Everton Reihenfolge der Bücher

The study focuses on the antioxidant properties of Ocimum citriodurum, revealing that rosmarinic acid is the predominant compound in its hydroalcoholic extract. Utilizing HPLC-MS, researchers identified seven chemical constituents and established an active potential of 0.547 for the extract's antioxidant activity. In vitro tests confirmed its efficacy with a 50% effective concentration of 50.53 mg/L against the DPPH method. Additionally, a Didactic Sequence was developed to teach about bioactive molecules and antioxidants, integrating findings with organic chemistry content.

The book explores the remarkable properties of essential oils from various plants, focusing on their antioxidant, anti-inflammatory, and anti-arthritic activities. It details the extraction and characterization of these oils through hydrodistillation and GC-MS analysis, identifying 48 chemical constituents, predominantly (E)-anethole. The study highlights the preparation of a low-energy phase inversion nanoemulsion, demonstrating significant efficacy in biological assays, suggesting that nanoencapsulated systems could enhance pharmacological applications.

The study explores the synthesis of silver nanoparticles (AgNPs) from Piper nigrum essential oil nanoemulsion, utilizing a phase inversion method and AgNO3 reduction. It highlights the chemical profile, with limonene as the primary component, and evaluates the antioxidant and anti-inflammatory activities of the AgNPs. Notably, the research found an IC50 value of 16.26 mg L-1 for antioxidant activity and 0.217 mg mL-1 for anti-inflammatory effects at pH 11, demonstrating the efficacy of P. nigrum AgNPs in enhancing these biological activities.

The study focuses on the innovative synthesis and evaluation of silver nanoparticles (AgNPs) derived from the hydroalcoholic extract of Passiflora edulis Sims seeds. Using cold maceration and HPLC-MS for chemical profiling, the research identified Genisteins as the primary constituent. AgNPs were synthesized through Ag+ reduction and characterized via UV-Vis spectrophotometry and DLS. The antioxidant activity was assessed using the ABTS method, revealing a notable CI50 of 9.23 mg L-1 at pH 4, highlighting the effectiveness of these nanoparticles and the influence of pH on their properties.

The study investigates the chemical and biological properties of Ixora coccinea L. through hydroalcoholic extracts and fractions. Using high-performance liquid chromatography coupled with mass spectrometry (HPLC/MS), catechol was identified as the predominant component. The research assessed antioxidant, anti-inflammatory, and anti-arthritic activities, revealing effective concentrations (EC50) that indicate strong biological activity across all assays. The antioxidant activity showed EC50 values between 6.45 and 87.15 ppm, while anti-inflammatory and anti-arthritic activities ranged from 32.27 to 198.06 ppm and 10.76 to 66.02 ppm, respectively.

The study focuses on the antioxidant properties of natural molecules from the hydroalcoholic extract of Ocimum citriodurum, identifying seven chemical constituents, primarily rosmarinic acid. Using HPLC-MS, the extract demonstrated significant antioxidant activity with an in silico active potential of 0.547 and an in vitro EC50 of 50.53 mg/L against the DPPH method. Additionally, the research led to the development of an educational Teaching Sequence on bioactive molecules and antioxidants, integrating Organic Functions into the curriculum through the PASS Online and PubChem resources.

Brazil boasts an impressive diversity of plant species, estimated between 50,542 and 60,042, across six distinct biomes. These include the lush Amazon rainforest, the central Cerrado savannah, the Atlantic Mata Atlântica, the arid Caatinga, the southern Pampa grasslands, and the unique Pantanal wetlands. This rich variety highlights Brazil's status as one of the most biodiverse countries globally, showcasing its ecological significance and the importance of preserving these unique environments.

The study investigates the larvicidal properties of essential oil and nanoemulsion derived from Coleus aromaticus Benth leaves against Aedes aegypti larvae. It reveals a significant phenolic content and promising antioxidant activity. The essential oil demonstrated larvicidal effects with an LC50 of 3.24 mg L-1, while the nanoemulsion exhibited even greater efficacy at 1.83 mg L-1. These findings suggest the potential of both products as biocontrol agents in combating Aedes aegypti, highlighting the market viability of the nanoemulsion.

O teor total de fenol foi de 252,35 mg EAT g-1 para C. limonia e L. nobilis EO, o que é um resultado significativo para as actividades farmacológicas. No teste de actividade antioxidante, um EC50 de 85,20 mg L-1, EC50 de 77,23 mg L-1, EC50 de 88,13 mg L-1, EC50 de 45,30 mg L-1 para a acção de EO e nanoemulsões (NHE 1, NHE 2 e NHE 3) de C. limonia e L. nobilis, respectivamente, foram classificados como acção promissora. O óleo essencial estudado obtido por cruzamento e as suas nanoemulsões (NHE 1, NHE 2 e NHE 3) mostraram um potencial anti-inflamatório, com um EC50 de 161,84 mg L-1, um EC50 de 220,07 mg L-1, um EC50 de 186,85 mg L-1 e um EC50 de 252,67 mg L-1, respectivamente. Através dos resultados obtidos, confirmou-se a acção antioxidante e anti-inflamatória do óleo obtido pelo cruzamento das espécies de C. limonia e L. nobilis e um aumento do seu potencial quando o óleo é incorporado em nanoemulsões. Proporcionando resultados expressivos e inovadores, dada a sua ausência na literatura, a sua aplicação é apreciada e são encorajados mais estudos devido ao seu potencial biotecnológico.

P. guajava leaves and essential oil obtained by hydrodistillation technique were collected. Chemical constituents were evaluated by gas chromatography-mass spectrometry (GC/MS). The total phenolic content was quantified by the Folin-Ciocalteau spectrophotometric method. For the toxicity test, the Artemia salina bioassay was applied. The nanoemulsion (W/A) was prepared using the low energy phase inversion method. The LC50 was calculated for the action of the nanoemulsion against Aedes aegypti larvae by the Probit method. The main chemical constituent found in the essential oil of P. guajava was -pinene 34.25%. Total phenolic compounds were quantified as 210.35 mg EAT g-1. In the toxicity bioassay, the LC50 of 323.6 mg L-1 was classified as non-toxic. The nanoemulsion droplets after 30 days of handling had an average size of 120.41 ± 0.55 nm. The larvicidal activity of the nanoemulsion showed mortality at concentrations of 10 to 100 mg L-1 with an LC50 of 12.75 mg L-1.